Greg's group primarily uses transcriptomic studies to elucidate the genetic basis of risk for Crohn’s disease and ulcerative colitis (with Subra Kugathasan at Emory), understand plasma cell development via single cell genomics (with Eun Lee at Emory), and study fundamental aspects of gene regulation using evolutionary and genome engineering approaches.
- On the utilization of polygenic risk scores for therapeutic targeting.
- Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation.
- Differential transcriptome and development of human peripheral plasma cell subsets.
- Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study.
- Stenger et al (2016): Bone Marrow Derived Mesenchymal Stromal Cells from Sickle Cell Disease Patients Display Intact Immune and Hematopoietic Functionality [.xlsx]
- Zhao et al (2016): A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood
- Tabasssum et al (2015): Omic Personality: The Longitudinal Consistency of Transcriptional, Epigenetic and Clinical Profiles
- Lee et al (2014): Combined transcriptomics and metabolomics in a rhesus macaque drug administration study
- Shehata et al, (2014): Identification of NDUFB11 mutations in Histiocytoid Cardiomyopathy
- Rojas-Peña et al (2014): Differential gene expression in craniosynostosis
- Kim et al (2014): Gene expression profiles associated with acute myocardial infarction and risk of cardiovascular death
- Preininger et al (2013): Blood-Informative Transcripts Define Nine Common Axes of Peripheral Blood Gene Expression
- Qin et al (2013): Effect of Normalization on Statistical and Biological Interpretation of Gene Expression Profiles
- Zhang et al (2013): Complex Genetic Architecture of Cardiac Disease in a Wild Type Inbred Strain of Drosophila melanogaster
- Reed et al (2013): Systems genomics of metabolic phenotypes in Drosophila